In the broad horizon of the Great American Chaco, the Palo Santo Private Reserve, where is the John Burton Research Station, emerges as a conservation stronghold in the center of the Chaco plain that, despite its extreme climatic conditions, is a sanctuary of life, housing a unique diversity of flora and fauna, where Indigenous cultures find their home. The Palo Santo Private Reserve, more than a natural refuge, is also a testimony of human commitment to conservation, a legacy that finds its voice in the figure of John Burton.